Gene interactions and pathways from curated databases and text-mining

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ERBB2 — MUC1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Scibetta et al., DNA Cell Biol 2001 (Breast Neoplasms) : Regulation of MUC1 expression in human mammary cell lines by the c-ErbB2 and ras signaling pathways
Adriance et al., Oncogene 2004 (Mammary Neoplasms, Experimental) : We found that transient transfection of activated ErbB2 into human embryonic kidney 293/MUC1 cells resulted in the repression of MUC1 expression ... Further, transient transfection of activated ErbB2 resulted in the inhibition of Muc1 transcriptional activation in luciferase reporter assays ... These data suggest that the activation of ErbB2 , which only occurs in c-Neu tumors, selectively inhibits Muc1 expression