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IFNG — IL18BP

Text-mined interactions from Literome

Yoshino et al., Mol Hum Reprod 2001 : On the other hand, IFN-gamma up-regulated the IL-18BP expression both in cultured epithelial cells and stromal cells
Faggioni et al., J Immunol 2001 (Granuloma...) : In vitro, IL-18BP-Fc blocks IL-18 ( 100 ng/ml ) -induced IFN-gamma production by KG1 cells ( EC ( 50 ) = 0.3 microg/ml ) ... Given 10 min before LPS challenge to mice primed 12 days in advance with heat killed Propionibacterium acnes, IL-18BP-Fc prevents LPS induced liver damage and IFN-gamma and Fas ligand expression ... IL-18BP-Fc also prevents Con A-induced liver damage and IFN-gamma and Fas ligand expression as well as liver damage induced by Pseudomonas aeruginosa exotoxin A or by anti-Fas agonistic Ab
Im et al., J Interferon Cytokine Res 2002 : Recombinant rat IL-18BP binds to rat IL-18, reacts with antibodies to human or mouse IL-18BP, and inhibits IL-18 dependent interferon-gamma (IFN-gamma) production in vitro
Reznikov et al., J Interferon Cytokine Res 2002 : In PBMC stimulated with lypopolysaccharide (LPS) or in whole blood stimulated with Staphylococcus epidermidis, 3 nM IL-18BP reduced IFN-gamma by 80 %, whereas IL-18Ralpha : Fc had no effect
Bufler et al., Proc Natl Acad Sci U S A 2002 : In testing whether IL-1F7b interacts with IL-18BP, we unexpectedly observed that IL-1F7b enhanced the ability of IL-18BP to inhibit IL-18 induced IFNgamma by 25-30 % in a human natural killer cell line
Möller et al., Rheumatology (Oxford) 2003 (Arthritis...) : Interferon-gamma induces expression of interleukin-18 binding protein in fibroblast-like synoviocytes
Stuyt et al., Cytokine 2003 : IL-18BP reduced S. epidermidis induced IFN-gamma ( 77 % maximal suppression )
Bachmann et al., J Cell Mol Med 2009 : IL-18BP is strongly up-regulated by IFN-gamma , thereby establishing a negative feedback mechanism detectable in cell culture and in vivo
Nold-Petry et al., PloS one 2010 (Lymphohistiocytosis, Hemophagocytic) : Failure of interferon gamma to induce the anti-inflammatory interleukin 18 binding protein in familial hemophagocytosis