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SETD2 — SLC22A3

Text-mined interactions from Literome

Cheng et al., PloS one 2011 (Anoxia...) : These results suggest that hypoxia or overexpression of HIF-1a induces the EMT that is largely dependent on NF-?B in pancreatic cancer cells
Han et al., Biochim Biophys Acta 2013 (Anoxia) : As hypoxia-inducible factor (HIF)-1a is found to mediate TGF-ß1 induced signaling pathway, we tested the hypothesis that HIF-1a and its upstream regulator prolyl hydroxylase domain containing proteins ( PHDs ) are involved in TGF-ß1 induced EMT using cultured renal tubular cells ... Meanwhile, we found that TGF-ß1 time-dependently increased HIF-1a and that HIF-1a siRNA significantly inhibited TGF-ß1 induced EMT, suggesting that HIF-1a mediated TGF-ß1 induced-EMT
Zhang et al., BMC cancer 2013 (Anoxia...) : We demonstrated that hypoxia stabilized HIF1a promoted EMT through increasing SNAI1 transcription in HCC cells
Lan et al., Int J Oncol 2013 : Overexpression of HIF-1a induced FTC133 cells to undergo EMT , downregulated the epithelial markers E-cadherin, upregulated the mesenchymal marker vimentin, and associated with highly invasive and metastatic properties
Lan et al., Zhonghua Yi Xue Za Zhi 2013 (Thyroid Neoplasms) : Overexpression of HIF-1a induced FTC133 cells to undergo EMT