Gene interactions and pathways from curated databases and text-mining

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BCL6 — MYLIP

Text-mined interactions from Literome

Lin et al., Leukemia 2011 (Lymphoma, B-Cell) : We identify that, on cell adhesion to FDC, FDC induces upregulation of PRDM1 expression through downregulation of miR-9 and let-7 families and induces downregulation of BCL-6 through upregulation of miR-30 family in B-lymphocytes and lymphoma cells ... We further demonstrate that the miR-30 family directly controls BCL-6 expression and miR-9-1 and let-7a directly control PRDM-1 expression through targeting their 3'UTR, mediating the FDC effect
Pan et al., PloS one 2012 : Furthermore, in BRL-3A rat liver cells, we observed that overexpression of miR-127 significantly suppressed cell growth and directly inhibited the expression of Bcl6 and Setd8
Nazari-Jahantigh et al., J Clin Invest 2012 (Atherosclerosis...) : Additionally, we found that miR-155 directly repressed expression of BCL6 , a transcription factor that attenuates proinflammatory NF-?B signaling
Basso et al., J Exp Med 2012 : Similarly, the expression of additional genes relevant for the GC phenotype, including SPI1, IRF8, and MYB, appears to be sustained via BCL6 mediated repression of miR-155
Sandhu et al., Proc Natl Acad Sci U S A 2012 (Leukemia, Lymphoid) : We show that Bcl6 is indirectly regulated by miR-155 through Mxd1/Mad1 up-regulation
Sawant et al., Mol Immunol 2013 (Inflammation) : Bcl6 represses and Stat3 activates miR-21 transcription through a Stat3 binding element in the promoter, indicating opposing regulation of miR-21 by the two transcription factors via the same DNA site
Guo et al., Molecules (Basel, Switzerland) 2012 (Pancreatic Neoplasms) : Overexpression of miR-491-5p in the pancreatic cancer cell line SW1990 effectively inhibited both endogenous Bcl-XL and TP53 gene expressions
Dai et al., Nan Fang Yi Ke Da Xue Xue Bao 2013 : CONCLSUION : Hsa-miR9 positively regulate the expression of BCL-6 and apoptosis of EBV ( + ) Raji cells and EBV ( - ) Ramous cells