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MYLIP — SOCS1

Text-mined interactions from Literome

Lu et al., Immunity 2009 : Moreover, miR155 deficiency in Treg cells resulted in increased suppressor of cytokine signaling 1 ( SOCS1 ) expression accompanied by impaired activation of signal transducer and activator of transcription 5 ( STAT5 ) transcription factor in response to limiting amounts of interleukin-2
Wang et al., J Biol Chem 2009 : Transfection of miR-155 attenuated the expression of Suppressor of Cytokine Signal (SOCS)-1 and enhanced the expression of iNOS
Androulidaki et al., Immunity 2009 : In silico analyses and transfection studies revealed that let-7e repressed Toll-like receptor 4 (TLR4), whereas miR-155 repressed SOCS1 , two proteins critical for LPS-driven TLR signaling, which regulate endotoxin sensitivity and tolerance
Martinez-Nunez et al., J Biol Chem 2011 (Asthma) : Finally we also demonstrate that miR-155 affects the IL-13 dependent regulation of several genes ( SOCS1 , DC-SIGN, CCL18, CD23, and SERPINE ) involved in the establishment of an M2/pro-Th ( 2 ) phenotype in macrophages
Vaporidi et al., Am J Physiol Lung Cell Mol Physiol 2012 (Disease Models, Animal...) : In the inflammatory network, IL-6 and SOCS-1 , regulated by miRNAs let-7 and miR-155 , respectively, appeared as central nodes
Zhao et al., PloS one 2013 (Carcinoma, Squamous Cell...) : Whereas overexpression of miR-155 inhibited SOCS1expression , elevated STAT3 expression, and promoted hep-2 cells growth, migration and invasion
Zhou et al., J Am Soc Nephrol 2013 (Fibrosis...) : Overexpression of miR-150 significantly reduced expression of the antifibrotic protein suppressor of cytokine signaling 1 ( SOCS1 ) and upregulated profibrotic proteins in both proximal tubular and mesangial cells