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MYLIP — WEE1

Text-mined interactions from Literome

Wuchty et al., PloS one 2011 (Brain Neoplasms...) : Our analysis predicted a significant association between miR-128 and the protein kinase WEE1, which we subsequently validated experimentally by showing that the over-expression of the naturally under expressed miR-128 in glioma cells resulted in the inhibition of WEE1 in glioblastoma cells
Bhattacharya et al., Oncogene 2013 (Melanoma...) : Regulation of cell cycle checkpoint kinase WEE1 by miR-195 in malignant melanoma ... Taken together, the present study shows that WEE1 expression in malignant melanoma is directly regulated by miR-195 ... miR-195 mediated downregulation of WEE1 in metastatic lesions may help to overcome cell cycle arrest under stress conditions in the local tissue microenvironment to allow unrestricted growth of tumour cells
Chen et al., J Chemother 2013 (Carcinoma, Renal Cell...) : miR-381 , a novel intrinsic WEE1 inhibitor , sensitizes renal cancer cells to 5-FU by up-regulation of Cdc2 activities in 786-O