Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
FOXO3
→
IL2RA
(decreases, IL2RA Activity, FOXO3 Activity)
Asselin-Labat et al., Blood 2004* Evidence: characterized the human gilz promoter and showed that FoxO3 (Forkhead box class O3) binding to the Forkhead responsive elements identified in the promoter is necessary for induction of gilz expression upon IL-2 withdrawal.