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FASLG — IL10

Text-mined interactions from Literome

Saito et al., J Immunol 1999 (Sjogren's Syndrome) : Transgenic expression of IL-10 induced apoptosis of glandular tissue destruction and lymphocyte infiltration consisting primarily of Fas-ligand (FasL)+ CD4+ T cells, as well as in vitro up-regulation of FasL expression on T cells
Arnold et al., J Immunol 1999 : Stimulation of the cells with IL-6, IL-10, IL-12, TGF-beta1, and GM-CSF did not modulate the constitutive FasL expression, but IFN-gamma mediated FasL up-regulation was significantly diminished by IL-10 and TGF-beta1, respectively
Saito et al., Crit Rev Immunol 2000 (Autoimmune Diseases...) : Using targeted introduction of this molecule into the exocrine gland epithelial cells, we found that IL-10 induced apoptosis of glandular tissues destruction and lymphocyte infiltration consisting primarily of Fas-ligand+ CD4+ T cells, as well as in vitro upregulation of FasL expression on T cells
Daigle et al., Eur J Immunol 2000 (Inflammation) : Fas ligand induced IL-10 production in monocytes might represent an important anti-inflammatory mechanism in secondary immune responses
Ruan et al., Immunology 2001 (Respiratory Syncytial Virus Infections) : Previous data indicated that IL-10 induces Fas ligand (L) expression on mouse T cells
Lundy et al., Infect Immun 2002 (Schistosomiasis mansoni) : These results suggest that FasL expressing, splenic B-1a cells are important mediators of SEA stimulated CD4 ( + ) -T-cell apoptosis and that maximal FasL expression on B-1a cells is dependent on antigenic stimulation and the presence of IL-4 and IL-10
Duan et al., Clin Cancer Res 2004 (Osteosarcoma) : The purpose of these studies was to determine whether alkylating agents affect the expression of Fas ligand (FasL) and whether interleukin 12 enhances the sensitivity of human OS cells to alkylating agents
Wang et al., World J Gastroenterol 2004 : To investigate the effects of platelet derived growth factor ( PDGF ) and interleukin-10 (IL-10) on Fas/Fas-ligand and Bcl-2/Bax mRNA expressions in rat hepatic stellate cells
Zhang et al., World J Gastroenterol 2006 (Liver Cirrhosis) : The expression of Fas and FasL is increased in the course of liver fibrosis, and is further increased by IL-10
Zhang et al., Med Chem 2006 (Liver Cirrhosis) : The effects of interleukin-10 on the expression of Fas and FasL in rat hepatic stellate cells ... To study the effects of interleukin-10 on the expression of fas and fasL in hepatic stellate cells in experimental rat hepatic fibrosis
Guillermo et al., J Leukoc Biol 2007 (Chagas Disease) : Anti-FasL , but not anti-TNF-alpha or anti-TRAIL, blocked activation induced cell death of CD8 T cells and increased secretion of IL-10 and IL-4 by CD4 T cells from T. cruzi infected mice
Seitz et al., Shock 2011 (Inflammation...) : Fas ligand stimulation further enhanced IL-6 and suppressed IL-10 release in AMFs after trauma.The results indicate that the Fas/FasL system is activated after chest trauma, and FasL is associated with the inflammatory response after lung contusion