Gene interactions and pathways from curated databases and text-mining

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ACE — FGFR3

Text-mined interactions from Literome

Singh et al., Comp Biochem Physiol C Toxicol Pharmacol 2002 : Acute effects of Ace , Meth and IL-1 on AChE activity, ACh and CRF mRNA levels in, and CRF-release from the hypothalamus were studied in vitro
Jamal et al., Brain Res 2005 : The effect of high acetaldehyde (ACe) on acetylcholine (ACh) release was studied in vivo in the medial frontal cortex ( mfc ) of freely moving rats using brain microdialysis coupled with high performance liquid chromatography and an electrochemical detector ... The present study suggests that both EtOH and ACe concentration in the brain can decrease in vivo ACh release in the mfc of free moving rats, and the ACe induced decrease in ACh levels was significantly higher than EtOH
O'Driscoll et al., J Clin Invest 1997 (Diabetes Mellitus, Type 1) : Acute ACE inhibition ( with intrabrachial enalaprilat ) enhanced ACh responses in the diabetic patients ( P < 0.005 ), with a further improvement evident after 1 mo of oral therapy with enalapril ( P < 0.001 ) when ACh responses were normalized