Gene interactions and pathways from curated databases and text-mining

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CDC42 — ROCK1

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

de Toledo et al., PloS one 2012 : Cooperative anti-invasive effect of Cdc42/Rac1 activation and ROCK inhibition in SW620 colorectal cancer cells with elevated blebbing activity
Hirose et al., J Cell Biol 1998 (Neuroblastoma) : The neurite outgrowth by the p160ROCK inhibition was blocked by coexpression of dominant negative forms of Cdc42 and Rac, indicating that p160ROCK constitutively and negatively regulates neurite formation at least in part by inhibiting activation of Cdc42 and Rac
Tominaga et al., EMBO J 1998 : Expression of a dominant interfering p160ROCK inhibited RhoA-, but not Cdc42- or Rac-activation of NEH1