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LEP — LIF

Text-mined interactions from Literome

Fukuda et al., Fertil Steril 2003 : The effects of leptin on the production of IL-6, IL-11, leukemia inhibitory factor (LIF) , IL-8, growth regulated oncogene ( GRO ) -alpha, monocyte chemoattractant protein (MCP)-1, and macrophage inflammatory protein (MIP)-3alpha by ESC and the endometrial epithelial cell line HHUA were investigated
Quinton et al., Am J Reprod Immunol 2003 : The effect of leptin on cell growth and on the production of cytokines [Leukaemia Inhibitory Factor (LIF) , interleukin 6 and tumour necrosis factor-alpha ] and matrix metalloproteinases ( MMP ) ( MMP2 and MMP-9 ) was also investigated
Gonzalez et al., Endocrinology 2004 : Leptin induced increase in leukemia inhibitory factor and its receptor by human endometrium is partially mediated by interleukin 1 receptor signaling ... The present study was designed to investigate whether leptin can directly regulate the expression of LIF and its receptor (LIF-R) in human endometrial cells and/or whether leptin induced effects are linked to, or regulated in part by IL-1 signaling
Ramos et al., Endocrinology 2005 : Disruption of leptin signaling resulted in a significant reduction of IL-1 receptor type I, leukemia inhibitory factor , vascular endothelial growth factor receptor 2, and beta3-integrin levels
Carino et al., Int J Cancer 2008 (Adenocarcinoma...) : Remarkably, leptin induces a greater increase in VEGF/VEGFR2 and LIF levels in cancer than in benign cells ... Leptin induction of cytokines/receptors generally involved JAK2 and MAPK activation, but PI-3K phosphorylation was required for leptin increase of LIF , IL-1/IL-1R tI