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CD55 — IGF1

Text-mined interactions from Literome

Wolff et al., Cell 2006 : In C. elegans, the sole insulin/IGF-1 receptor, DAF-2, negatively regulates the FOXO transcription factor, DAF-16
Hansen et al., PLoS Genet 2008 : Long lived daf-2 insulin/IGF-1 receptor mutants require both autophagy and the transcription factor DAF-16/FOXO for their longevity, but we find that autophagy takes place in the absence of DAF-16
Kenyon et al., Ann N Y Acad Sci 2010 : However, the mechanisms by which inhibition of insulin/IGF-1 signaling and germline loss activate DAF-16/FOXO are distinct