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SERPINF1 — TP53

Text-mined interactions from Literome

Sasaki et al., Oncogene 2005 (Colorectal Neoplasms...) : We discovered that the expression of pigment epithelium derived factor (PEDF) was specifically induced by either p63 or p73, but not by p53
Ho et al., Cardiovasc Res 2007 : PEDF sequentially induced PPARgamma and p53 expression as observed in immunoblotting and immunofluoresence assays ... PEDF also increased the transcriptional activity of PPARgamma as evident from electromobility shift assays, and p53 as determined by the phosphorylation and acetylation of p53 and the induction of Bax ... The induction of p53 by PEDF was abolished by either PPARgamma antagonist or PPARgamma siRNA ... Our observations indicate that PEDF induces HUVECs apoptosis through the sequential induction of PPARgamma and p53 overexpression