Gene interactions and pathways from curated databases and text-mining

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JAK3 — TPO

Text-mined interactions from Literome

Wang et al., Blood 2000 : Previous studies indicated that Janus kinase ( JAK ) and its substrates mediate the effects of TPO on cellular proliferation and survival
Kuter et al., Int J Hematol 2013 : TPO binds the TPO receptor, activates JAK and STAT pathways, thus stimulating megakaryocyte growth and platelet production
Leven et al., Blood Cells Mol Dis 1997 : Studies on protein phosphorylation revealed that IL6, but not TPO , stimulated phosphorylation of JAK1, JAK2 and MAP kinase