Gene interactions and pathways from curated databases and text-mining

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IGFBP7 — VEGFA

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Dahlfors et al., Endocrinology 2000 : In conclusion, vascular endothelial growth factor and transforming growth factor-beta1 regulate IGFBP expression in bovine aortic endothelial cells
Liu et al., Oncogene 2007 (Neovascularization, Pathologic...) : In vitro, IGFBP-3 inhibited both vascular endothelial growth factor- and IGF stimulated human umbilical vein endothelial cells vascular network formation in a matrigel assay
Tamura et al., Eur J Pharmacol 2009 : IGFBP7 attenuated VEGF enhanced cyclooxygenase (COX)-2 and VEGF mRNA expression, and prostaglandin E ( 2 ) secretion
Chen et al., J Exp Clin Cancer Res 2010 (Melanoma, Experimental...) : The inhibition of MM growth was proved owing to apoptosis and reduced expression of VEGF induced by pcDNA3.1-IGFBP7