◀ Back to VEGFA

PRL — VEGFA

Text-mined interactions from Literome

Malaguarnera et al., J Cell Biochem 2004 : Prolactin increases HO-1 expression and induces VEGF production in human macrophages ... Furthermore, to determine whether PRL induced HO-1 activity was required for VEGF production by macrophages, the effect of PRL on the induction of VEGF was studied in the presence of an inducer stannic chloride ( SnCl ( 2 ) ) and of an inhibitor stannic mesoporphyrin ( SnMP ) of HO activity
Goldhar et al., Mol Cell Endocrinol 2005 : Prolactin induced expression of vascular endothelial growth factor via Egr-1 ... Given the functions of prolactin (PRL) during these stages and the supporting role of the vasculature, we investigated the regulation of VEGF by PRL ... The induction of VEGF by PRL was PRL receptor-, Jak2- and MAP kinase kinase dependent ... Our results indicate that PRL induces VEGF expression through Egr-1, and implicates VEGF as an intermediary of PRL regulated angiogenesis