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APOE — IL12B
Text-mined interactions from Literome
Iacobelli-Martinez et al., J Virol 2005
(Adenoviridae Infections) :
Subgroup B ( Ad16 and -35 ) and Ad37, but not
Ad2 or -5, significantly
reduced IL-12 production by human peripheral blood mononuclear cells stimulated with gamma interferon ( IFN-gamma ) and lipopolysaccharide
Wei et al., Neurobiol Dis 2013
:
We observed that the absence of
apoE resulted in the increased proportion of Th1 and Th17 cells in the spleens and brains, as well as up-regulated expressions of proinflammatory cytokines ( IL-17, IFN-?, TNF-a,
IL-12 , IL-1ß and IL-6 ) and transcription factors ( ROR?t and T-bet ) in the CNS