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ID2 — NEUROD4
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Bai et al., Dev Cell 2007
:
Overexpression of
Id2 in the chick hindbrain upregulates Hes1 expression and
inhibits proneural gene expression and
neuronal differentiation
Zhang et al., Brain Res 2010
:
Our results demonstrated that Mash1, Id2, Hes1 were all widely expressed in in vitro progenies from mouse SVZa NPCs. Analyses of SVZa NPCs transfected with eukaryotic expression plasmids showed that Mash1 promoted neuronal differentiation from SVZa NPCs, while
Id2 and Hes1
repressed neuronal differentiation