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HDAC2 — SRC
Text-mined interactions from Literome
Kostyniuk et al., Oncogene 2002
:
Sodium butyrate and Trichostatin A strongly inhibited activity of each of these highly disparate SRC promoters, demonstrating
histone deacetylase inhibitors directly
repress SRC transcription
Dehm et al., Biochem Cell Biol 2004
(Neoplasms) :
Interestingly,
histone deacetylase (HDAC) inhibitors, agents with well documented anti-cancer activity,
repress SRC transcription in a wide variety of human cancer cell lines ... Interestingly,
histone deacetylase (HDAC) inhibitors, agents with well documented anti-cancer activity,
repress SRC transcription in a wide variety of human cancer cell lines
Takizawa et al., Drug Metab Dispos 2010
:
HDAC inhibitors diminished the binding between CAR and HDAC1 and
augmented the binding of
steroid receptor coactivator-1 (SRC-1) to CAR