Yasuda et al., Lab Invest 2003
(Arthritis, Rheumatoid) :
Integrin alpha4beta1 may be partially involved in the MMP induction by COOH-HBFN-f
Huhtala et al., J Cell Biol 1995
:
In contrast, peptide V from the heparin binding region, shown previously to stimulate focal contact formation, further enhanced MMP expression by RSF when present on the substrate with 120FN. RSF expressed alpha 4 beta 1 integrin , the receptor for CS-1, and the anti-alpha 4 mAb blocked the ability of CS-1 to suppress MMP induction by 120FN