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PON1 — TNF

Text-mined interactions from Literome

Kumon et al., Life Sci 2003 : To clarify this point, we evaluated the transcriptional regulation of PON1 gene by IL-1beta, IL-6 and TNF-alpha in HepG2 cells using luciferase reporter gene assay
You et al., Dig Dis Sci 2009 (Colitis...) : ROS in the colon, the level of interleukin 1 beta (IL-1 beta) in colonic mucosa, serum tumor necrosis factor a ( TNF-alpha ), MPO, and MDA were significantly increased in DSS treated animals ( P < 0.01 ), with decreased PON1 activity ( P < 0.01 )
Feingold et al., Atherosclerosis 1998 (Acute-Phase Reaction) : Additionally, TNF and IL-1 treatment of HepG2 cells results in a decrease in PON mRNA levels indicating that these cytokines are capable of directly affecting liver cells