◀ Back to IL2
IL2 — TNFSF13B
Text-mined interactions from Literome
Huard et al., J Immunol 2001
:
Indeed,
BAFF is
sufficient to induce
IL-2 secretion and T cell division, when added to an anti-TCR stimulation
Xu et al., Acta Biochim Biophys Sin (Shanghai) 2007
(Lung Neoplasms...) :
It was found that CD3 positive T lymphocytes ( including CD4, CD8, and part of CD25 and CD69 positive cells ) of MPE in lung cancer highly and consistently expressed the BAFF molecule, while high expressions of
BAFF could only be found in phytohemagglutinin ( PHA ) or
interleukin 2 (IL-2) induced T lymphocytes from NMPE or healthy controls
Suzuki et al., Cytokine 2008
:
Effect of
interleukin-2 on synthesis of
B cell activating factor belonging to the tumor necrosis factor family ( BAFF ) in human peripheral blood mononuclear cells ... We found
interleukin-2 (IL-2) strongly and dose-dependently
stimulated BAFF synthesis in PBMCs, and an anti-IL-2 antibody neutralized the effect ... Persistent over production of
IL-2 might
lead to up-regulation of
BAFF synthesis in PBMCs in pathological conditions such as lupus
Wang et al., Frontiers in bioscience (Landmark edition) 2013
(Multiple Myeloma) :
Furthermore, BLyS, together with
IL-2 and IL-6, significantly
promoted MM cell proliferation and
BLyS receptor expression compared with that in the control group