Gene interactions and pathways from curated databases and text-mining

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IL2 — TNFSF13B

Text-mined interactions from Literome

Huard et al., J Immunol 2001 : Indeed, BAFF is sufficient to induce IL-2 secretion and T cell division, when added to an anti-TCR stimulation
Xu et al., Acta Biochim Biophys Sin (Shanghai) 2007 (Lung Neoplasms...) : It was found that CD3 positive T lymphocytes ( including CD4, CD8, and part of CD25 and CD69 positive cells ) of MPE in lung cancer highly and consistently expressed the BAFF molecule, while high expressions of BAFF could only be found in phytohemagglutinin ( PHA ) or interleukin 2 (IL-2) induced T lymphocytes from NMPE or healthy controls
Suzuki et al., Cytokine 2008 : Effect of interleukin-2 on synthesis of B cell activating factor belonging to the tumor necrosis factor family ( BAFF ) in human peripheral blood mononuclear cells ... We found interleukin-2 (IL-2) strongly and dose-dependently stimulated BAFF synthesis in PBMCs, and an anti-IL-2 antibody neutralized the effect ... Persistent over production of IL-2 might lead to up-regulation of BAFF synthesis in PBMCs in pathological conditions such as lupus
Wang et al., Frontiers in bioscience (Landmark edition) 2013 (Multiple Myeloma) : Furthermore, BLyS, together with IL-2 and IL-6, significantly promoted MM cell proliferation and BLyS receptor expression compared with that in the control group