UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

NCI Pathway Database IL1-mediated signaling events: IRAK/TRAF6/TAK1/TAB1/TAB2 complex (IRAK1-TRAF6-MAP3K7-TAB1-TAB2) → UBC13/UEV1A complex (UBE2N-UBE2V1) (modification, collaborate)
Takaesu et al., Mol Cell 2000, Wang et al., Nature 2001, Jiang et al., Mol Cell Biol 2002
Evidence: mutant phenotype, assay
NCI Pathway Database IL1-mediated signaling events: UBC13/UEV1A complex (UBE2N-UBE2V1) → TRAF6/TAK1/TAB1/TAB2 complex (TRAF6-MAP3K7-TAB1-TAB2) (modification, activates)
Takaesu et al., Mol Cell 2000, Wang et al., Nature 2001, Jiang et al., Mol Cell Biol 2002
Evidence: mutant phenotype, assay
NCI Pathway Database IL1-mediated signaling events: IRAK/TRAF6/TAK1/TAB1/TAB2 complex (IRAK1-TRAF6-MAP3K7-TAB1-TAB2) → UBC13/UEV1A complex (UBE2N-UBE2V1) (modification, collaborate)
Takaesu et al., Mol Cell 2000, Wang et al., Nature 2001, Jiang et al., Mol Cell Biol 2002
Evidence: mutant phenotype, assay
NCI Pathway Database IL1-mediated signaling events: UBC13/UEV1A complex (UBE2N-UBE2V1) → TRAF6/TAK1/TAB1/TAB2 complex (TRAF6-MAP3K7-TAB1-TAB2) (modification, activates)
Takaesu et al., Mol Cell 2000, Wang et al., Nature 2001, Jiang et al., Mol Cell Biol 2002
Evidence: mutant phenotype, assay