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ALB — ECM2
Text-mined interactions from Literome
Brill et al., Eur J Cell Biol 2002
:
Adult hepatocytes
ECM strongly
induced expression of both
albumin and HNF-4 in adult hepatocytes
Baricos et al., Experimental biology and medicine (Maywood, N.J.) 2003
:
Taken together, these results document the importance of tPA versus uPA in renal plasmin production and indicate that in contrast to elevated glucose, glycated
albumin may
contribute to
ECM accumulation in diabetic nephropathy
Stephan et al., Am J Nephrol 2004
:
We demonstrate that human
albumin stimulates the accumulation of
ECM proteins by proximal tubular epithelial cells through a post-transcriptional mechanism ... Taken together, our data suggest that
ECM protein accumulation in
response to
albumin resulted partly from inhibition of ECM degradation ... Addition of transforming growth factor beta ( TGF-beta ) -specific neutralizing antibody failed to alter ECM protein levels after albumin treatment, indicating that the
albumin induced increase in
ECM is TGF-beta independent
Li et al., Biochem Biophys Res Commun 2010
(Diabetic Nephropathies) :
Therefore, in the present studies, we determined the mechanisms by which glycated albumin activates NADPH oxidase in primary rat mesangial cells and its contribution to glycated
albumin induced TGF-beta expression and
extracellular matrix protein production