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IL10 — MMP3
Text-mined interactions from Literome
Meisser et al., Mol Hum Reprod 1999
:
The aim of this study was to determine the
effects of tumour necrosis factor alpha (TNF),
interleukin-1 alpha (IL-1alpha), macrophage colony stimulating factor ( MCSF ) and transforming growth factor beta ( TGFbeta ) on the secretion of
matrix metalloproteinases ( MMP ) , human chorionic gonadotrophin ( HCG ) and fetal fibronectin ( fFN ) by purified first trimester cytotrophoblastic cells (CTB) in vitro
Wang et al., Chin Med J (Engl) 2001
:
Immunohistochemical study and in situ hybridization showed that
IL-10 inhibited NOS2 and
MMP3 expression
John et al., Exp Lung Res 2002
(Pneumonia, Bacterial...) :
The endogenous production of IL-10 in AM of patients with sarcoidosis and the MMP downregulation by exogenous IL-10 suggest an
involvement of
IL-10 in
MMP regulation
Bamba et al., J Gastroenterol 2003
:
Matrix metalloproteinase-3 secretion from human colonic subepithelial myofibroblasts :
role of
interleukin-17
Fleenor et al., Invest Ophthalmol Vis Sci 2003
:
In the trabecular meshwork ( TM ),
interleukin (IL)-1alpha is a potent
inducer of
MMP-3 expression
Sun et al., Connect Tissue Res 2003
(Arthritis, Rheumatoid) :
Furthermore, the
induction of the
MMP expression and activities by
interleukin-1 was suppressed by the oscillatory shear
Borghaei et al., Biochem Biophys Res Commun 2004
:
A 5T/6T polymorphic site in the matrix metalloproteinase-3 (MMP-3) promoter has been identified as a repressor element involved in inhibiting
induction of
MMP-3 transcription by
interleukin 1 ; and the 6T allele has been associated with decreased expression of MMP-3 as compared to the 5T allele
Inoue et al., Rheumatol Int 2005
(Osteoarthritis, Hip...) :
Induction of vascular endothelial growth factor and
matrix metalloproteinase-3 ( stromelysin ) by
interleukin-1 in human articular chondrocytes and synoviocytes
Perianayagam et al., Eur J Clin Invest 2005
(Uremia) :
We hypothesized that previously reported defective synthesis of
IL-10 by immunocompetent cells exposed to a uraemic milieu may be
due to impaired mitochondrial
membrane potential ( MMP )
Stewart et al., BMC molecular biology 2007
:
Interleukin-4 inhibition of
interleukin-1 induced expression of
matrix metalloproteinase-3 (MMP-3) is independent of lipoxygenase and PPARgamma activation in human gingival fibroblasts
Chang et al., Rheumatol Int 2007
(Chondrosarcoma) :
Activin A suppresses
interleukin-1 induced
matrix metalloproteinase 3 secretion in human chondrosarcoma cells
Hu et al., Zhonghua Xin Xue Guan Bing Za Zhi 2008
(Myocardial Infarction...) :
In vivo myocardial
IL-10 transfer
reduced myocardial
MMP and collagen expression and increasing the TIMP expression
Coussens et al., Immunology 2009
(Tuberculosis) :
We therefore determined the effects of 1alpha,25 ( OH ) ( 2 ) D ( 3 ) on expression, secretion and activity of a number of MMP and TIMP in M. tuberculosis infected human leucocytes ; we also investigated the effect of 1alpha,25 ( OH ) ( 2 ) D ( 3 ) on the secretion of
interleukin-10 (IL-10) and prostaglandin E ( 2 ) ( PGE ( 2 ) ), both transcriptional
regulators of
MMP expression
Wang et al., J Biol Chem 2010
:
Importance of protein-tyrosine phosphatase-alpha catalytic domains for interactions with SHP-2 and
interleukin-1 induced
matrix metalloproteinase-3 expression
Gotoh et al., Connect Tissue Res 2013
:
Extracellular ß-NAD ( + ) inhibits
interleukin-1 induced
matrix metalloproteinase-1 and -3 expression on human gingival fibroblasts
Stearns et al., Invasion Metastasis 1997
(Bone Neoplasms...) :
However
IL-10 may
inhibit the production of
matrix metalloproteases ( MMP ) and prevent the establishment of metastasis
Wagner et al., J Neurooncol 1998
(Brain Neoplasms...) :
In all but one cell line no
enhancement of
MMP expression by
IL-10 was detected