Gene interactions and pathways from curated databases and text-mining

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IL10 — MMP3

Text-mined interactions from Literome

Meisser et al., Mol Hum Reprod 1999 : The aim of this study was to determine the effects of tumour necrosis factor alpha (TNF), interleukin-1 alpha (IL-1alpha), macrophage colony stimulating factor ( MCSF ) and transforming growth factor beta ( TGFbeta ) on the secretion of matrix metalloproteinases ( MMP ) , human chorionic gonadotrophin ( HCG ) and fetal fibronectin ( fFN ) by purified first trimester cytotrophoblastic cells (CTB) in vitro
Wang et al., Chin Med J (Engl) 2001 : Immunohistochemical study and in situ hybridization showed that IL-10 inhibited NOS2 and MMP3 expression
John et al., Exp Lung Res 2002 (Pneumonia, Bacterial...) : The endogenous production of IL-10 in AM of patients with sarcoidosis and the MMP downregulation by exogenous IL-10 suggest an involvement of IL-10 in MMP regulation
Bamba et al., J Gastroenterol 2003 : Matrix metalloproteinase-3 secretion from human colonic subepithelial myofibroblasts : role of interleukin-17
Fleenor et al., Invest Ophthalmol Vis Sci 2003 : In the trabecular meshwork ( TM ), interleukin (IL)-1alpha is a potent inducer of MMP-3 expression
Sun et al., Connect Tissue Res 2003 (Arthritis, Rheumatoid) : Furthermore, the induction of the MMP expression and activities by interleukin-1 was suppressed by the oscillatory shear
Borghaei et al., Biochem Biophys Res Commun 2004 : A 5T/6T polymorphic site in the matrix metalloproteinase-3 (MMP-3) promoter has been identified as a repressor element involved in inhibiting induction of MMP-3 transcription by interleukin 1 ; and the 6T allele has been associated with decreased expression of MMP-3 as compared to the 5T allele
Inoue et al., Rheumatol Int 2005 (Osteoarthritis, Hip...) : Induction of vascular endothelial growth factor and matrix metalloproteinase-3 ( stromelysin ) by interleukin-1 in human articular chondrocytes and synoviocytes
Perianayagam et al., Eur J Clin Invest 2005 (Uremia) : We hypothesized that previously reported defective synthesis of IL-10 by immunocompetent cells exposed to a uraemic milieu may be due to impaired mitochondrial membrane potential ( MMP )
Stewart et al., BMC molecular biology 2007 : Interleukin-4 inhibition of interleukin-1 induced expression of matrix metalloproteinase-3 (MMP-3) is independent of lipoxygenase and PPARgamma activation in human gingival fibroblasts
Chang et al., Rheumatol Int 2007 (Chondrosarcoma) : Activin A suppresses interleukin-1 induced matrix metalloproteinase 3 secretion in human chondrosarcoma cells
Hu et al., Zhonghua Xin Xue Guan Bing Za Zhi 2008 (Myocardial Infarction...) : In vivo myocardial IL-10 transfer reduced myocardial MMP and collagen expression and increasing the TIMP expression
Coussens et al., Immunology 2009 (Tuberculosis) : We therefore determined the effects of 1alpha,25 ( OH ) ( 2 ) D ( 3 ) on expression, secretion and activity of a number of MMP and TIMP in M. tuberculosis infected human leucocytes ; we also investigated the effect of 1alpha,25 ( OH ) ( 2 ) D ( 3 ) on the secretion of interleukin-10 (IL-10) and prostaglandin E ( 2 ) ( PGE ( 2 ) ), both transcriptional regulators of MMP expression
Wang et al., J Biol Chem 2010 : Importance of protein-tyrosine phosphatase-alpha catalytic domains for interactions with SHP-2 and interleukin-1 induced matrix metalloproteinase-3 expression
Gotoh et al., Connect Tissue Res 2013 : Extracellular ß-NAD ( + ) inhibits interleukin-1 induced matrix metalloproteinase-1 and -3 expression on human gingival fibroblasts
Stearns et al., Invasion Metastasis 1997 (Bone Neoplasms...) : However IL-10 may inhibit the production of matrix metalloproteases ( MMP ) and prevent the establishment of metastasis
Wagner et al., J Neurooncol 1998 (Brain Neoplasms...) : In all but one cell line no enhancement of MMP expression by IL-10 was detected