Fortin et al., Blood 2001
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Although protein tyrosine phosphatase (PTP) inhibitors used in combination with other stimuli can induce interleukin 2 (IL-2) production in T cells, a direct implication of nuclear factor of activated T cells ( NFAT ) has not yet been demonstrated
Adachi et al., FEBS Lett 1994
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Here, we demonstrate the rapid activation of a leukocyte tyrosine phosphatase LC-PTP ( HePTP ) gene expression by IL-2 in an IL-2 dependent human T cell ILT-Mat