Sreeramaneni et al., Mol Cell Biol 2005
(Cell Transformation, Neoplastic) :
In cultured primary cells, the Dmp1 promoter was efficiently activated by oncogenic Ha-Ras ( V12 ), but not by overexpressed c-Myc or E2F-1 Inoue et al., Oncogene 2007
:
Dmp1 expression is repressed by physiological mitogenic stimuli as well as by overexpressed E2F proteins ; thus, it is a novel marker of cells that have exited from the cell cycle