Gene interactions and pathways from curated databases and text-mining

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ADM — IL6

Text-mined interactions from Literome

Udono et al., Invest Ophthalmol Vis Sci 2000 : Regulation of the ADM expression by basic fibroblast growth factor, interferon (IFN)-gamma, tumor necrosis factor-alpha, interleukin (IL)1beta , or all-trans-retinoic acid was studied
Hofbauer et al., Hypertension 2002 : For this purpose, we characterized the effects of inflammatory cytokines, tumor necrosis factor-alpha ( 100 microg/L ), interleukin-1beta ( 20 microg/L ), and interferon-gamma ( 0.5 U/L ) on ADM gene expression in rat aortic vascular smooth muscle cells ( AVSMCs )
Wong et al., Endocrinology 2005 (Inflammation) : ADM increased initial secretion of MIF and IL-1beta from both nonstimulated and LPS stimulated cells, and it also increased basal and LPS induced IL-6 secretion of the cells by 2- to 15-fold
Okura et al., Arthritis Res Ther 2008 (Arthritis, Experimental) : Adrenomedullin may thus be useful as a treatment for rheumatoid arthritis ; however, the effect of adrenomedullin on IL-6 production in the synovial tissue may be an undesirable adverse effect in rheumatoid arthritis therapy
Yildirim et al., Clin Exp Immunol 2010 : The effect of adrenomedullin and cold stress on interleukin-6 levels in some rat tissues