UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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LRPAP1 — SHH

Pathways - manually collected, often from reviews:

NCI Pathway Database Signaling events mediated by the Hedgehog family: SHH Np/Cholesterol complex (SHH) → LRPAP1 (LRPAP1) (modification, collaborate) McCarthy et al., J Biol Chem 2002 *
Evidence: assay, other species
NCI Pathway Database Signaling events mediated by the Hedgehog family: SHH Np/Cholesterol complex (SHH) → Megalin/LRPAP1 complex (LRP2-LRPAP1) (modification, collaborate)
McCarthy et al., J Biol Chem 2002 *
Evidence: assay, other species
NCI Pathway Database Signaling events mediated by the Hedgehog family: LRPAP1 (LRPAP1) → SHH Np/Cholesterol/Megalin complex (SHH-LRP2) (modification, collaborate)
McCarthy et al., J Biol Chem 2002 *
Evidence: assay, other species
NCI Pathway Database Signaling events mediated by the Hedgehog family: SHH Np/Cholesterol/Megalin complex (SHH-LRP2) → Megalin/LRPAP1 complex (LRP2-LRPAP1) (modification, collaborate)
McCarthy et al., J Biol Chem 2002 *
Evidence: assay, other species