Gene interactions and pathways from curated databases and text-mining

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IGF1 — MYC

Text-mined interactions from Literome

Mawson et al., Mol Cell Endocrinol 2005 (Breast Neoplasms) : Therefore, estrogen and insulin/IGF-1 differentially regulate c-Myc and cyclin D1 to cooperatively stimulate breast cancer cell proliferation
Sun et al., Oncogene 2009 : We found previously that in intestinal cells, insulin or insulin-like growth factor-1 stimulates c-Myc and cyclin D1 protein expression through both Akt dependent and Akt independent mechanisms
Pongsavee et al., International journal of molecular sciences 2009 : It is presumed that estrogen and insulin/IGF-1 regulate c-Myc and cyclin D1 during breast cancer cell proliferation