Gene interactions and pathways from curated databases and text-mining

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CAT — TYR

Text-mined interactions from Literome

Zhang et al., Arch Biochem Biophys 2001 : Catalase , a specific antioxidant for H2O2, decreased vanadate induced expression of p21 and Chk1, reduced phosphorylation of Cdc2Tyr15 , and decreased cyclin B1 levels
Inoue et al., Biochem Pharmacol 1990 (Melanoma) : The cytotoxicity of the former two amines was completely prevented by semicarbazide, an inhibitor of plasma monoamine oxidase, while that of the latter two was not prevented by semicarbazide, catalase , and phenylthiourea, a tyrosinase inhibitor
Lindbladh et al., Acta Derm Venereol 1983 : Ascorbic acid and 5-hydroxydopamine also inactivated tyrosinase , but with these compounds inactivation was completely prevented by addition of catalase
Karg et al., J Invest Dermatol 1993 (Melanoma) : Inhibition of intracellular catalase by 3-amino-1,2,4-triazole caused an increase in the tyrosinase level