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BCR — IFI27

Text-mined interactions from Literome

Gesbert et al., J Biol Chem 2000 : Second, inhibition of BCR/ABL kinase activity with the Abl tyrosine kinase inhibitor STI571 rapidly increases p27 ( Kip1 ) levels
Yang et al., Oncogene 2001 (Cell Transformation, Neoplastic) : Induction of p27 promoter activity followed BCR engagement of WEHI 231 cells, and this induction could be repressed upon co-transfection of a c-Myc expression vector
Banerji et al., Oncogene 2001 (Lymphoma, B-Cell...) : Furthermore, ectopic expression of a constitutively active form of AKT blocked the cell cycle arrest and apoptosis triggered by anti-IgM and also abrogated down-regulation of cyclin D2 and up-regulation of p27 ( Kip1 ) expression induced by BCR-engagement
Pierce et al., Hematol J 2001 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : This enhanced BCR/ABL mediated growth inhibition occurred over a range of growth factor concentrations and was independent of changes in p21 ( Cip1 ) and p27 ( Kip ) levels
Avramidou et al., Cell Death Differ 2007 : In contrast, short hairpin RNA ( shRNA ) -mediated downregulation of Swiprosin-1 impaired specifically spontaneous and BCR elicited apoptosis, but not BCR induced G1 cell cycle arrest and upregulation of the cell cycle inhibitor p27 ( Kip1 )
Chu et al., Leukemia 2010 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : Role of BCR-ABL-Y177 mediated p27kip1 phosphorylation and cytoplasmic localization in enhanced proliferation of chronic myeloid leukemia progenitors ... These studies show the importance of BCR-ABL-Y177-AKT mediated p27 phosphorylation in altered p27 localization and enhanced proliferation and expansion of primary CML progenitors