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CXCL5 — IFNG

Text-mined interactions from Literome

Hardaker et al., FASEB J 2004 (Inflammation...) : In primary cultured hASM cells taken from normal donors, CXCL10 protein expression was induced by IFN-gamma and TNF-alpha, cytokines reported as elevated in COPD, and a synergistic response was obtained when they were combined
Hillyer et al., Clin Exp Immunol 2003 : In combination with TNF-alpha, IFN-gamma suppressed CXCL8 but enhanced CCL5 and CXCL10, whereas transforming growth factor ( TGF ) -beta reduced secretion of all chemokines
Thomas et al., J Immunol 2004 (Bronchial Hyperreactivity) : In lymphocytes restimulated with CXCL9 and allergen in vitro, CXCL9 down-regulated IL-4 expression and up-regulated IFN-gamma expression, suggesting that CXCL9 is able to direct activated lymphocytes toward a Th1-type phenotype
Traidl-Hoffmann et al., Int Arch Allergy Immunol 2006 : Keratinocyte cultures established from normal skin of healthy donors were activated by IFN-gamma in the absence or presence of desloratadine and loratadine, and tested for the release of CCL5/RANTES, CXCL8/IL-8 , CCL17/TARC and CXCL10/IP-10 ... Desloratadine and loratadine inhibited the constitutive and IFN-gamma induced release of CCL5, CXCL8 and CXCL10 from keratinocytes, while the low release of CCL17 remained unchanged
Bandyopadhyay et al., Biochem Pharmacol 2006 : In addition, apigenin inhibits IFNgamma stimulated secretion of monokines, CXCL-9 , and -10 in MC3T3-E1 cells
Kanda et al., Endocrinology 2007 (MAP Kinase Signaling System...) : Prolactin enhances interferon-gamma induced production of CXC ligand 9 (CXCL9), CXCL10 , and CXCL11 in human keratinocytes ... Although prolactin alone was ineffective, it enhanced IFN-gamma induced secretion and mRNA expression of CXCL9, CXCL10 , and CXCL11 in parallel to the activation of STAT1, NF-kappaB, and IRF-1 ... These results suggest that prolactin may enhance IFN-gamma induced CXCL9, CXCL10 , and CXCL11 production in keratinocytes via activation of STAT1, NF-kappaB, and IRF-1 through JAK2 and MEK/ERK pathways
Kanda et al., Eur J Immunol 2007 : IL-18 enhances IFN-gamma induced production of CXCL9, CXCL10 , and CXCL11 in human keratinocytes ... We examined the in vitro effects of IL-18 on IFN-gamma induced CXCL9, CXCL10 , and CXCL11 production in human keratinocytes ... IL-18 enhanced the IFN-gamma induced secretion and mRNA expression of CXCL9, CXCL10 , and CXCL11 in parallel to the activation of NF-kappaB, STAT1, and IFN-regulatory factor (IRF)-1 ... These results suggest that IL-18 may potentiate IFN-gamma induced CXCL9, CXCL10 , and CXCL11 production in keratinocytes by activating NF-kappaB, STAT1, or IRF-1 through PI3 K/Akt and MEK/ERK pathways
Taubert et al., Vet Res Commun 2008 : Furthermore, IFNgamma-stimulation led to a strong upregulation in the transcription of VCAM-1, ICAM-1, CXCL10 and CCL2 genes and to a low to moderate increase in the E- and P-selectin, CXCL1, CXCL8 , CCL5, COX-2 and iNOS gene transcripts, but failed to enhance GM-CSF gene transcription
Milks et al., Liver Int 2009 (Disease Models, Animal...) : Ifng is dichotomous in the regulation of distinct chemokine subfamilies : specifically, Ifng is critical for overexpression of specific CXCL genes but dispensable for overexpression of specific CCL genes