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IL15 — JAK2

Text-mined interactions from Literome

Waldmann et al., Annu Rev Immunol 1999 (Autoimmune Diseases...) : In mast cells IL-15 signaling involves Jak2/STAT5 activation rather than the Jak1/Jak3 and STAT5/STAT3 system used in activated T cells
Pelletier et al., FEBS Lett 2002 : Furthermore, we found that IL-15 activates Jak-2 , p38 MAPK and ERK-1/2, but, unlike granulocyte macrophage-colony stimulating factor ( GM-CSF ), it does not activate signal transducer and activator of transcription ( STAT ) -5a/b
To et al., Br J Cancer 2004 (Cell Transformation, Neoplastic...) : The interleukin mediated Janus kinase ( JAK ) /STAT pathway plays a crucial role in carcinogenesis
Walker et al., Arch Virol Suppl 2005 (Ehrlichiosis) : Ehrlichiae attach to L-selectin and E-selectin, inhibit phagolysosomal fusion, apoptosis, and JAK/STAT activation, and downregulate IL-12, IL-15 , IL-18, TLR2 and 3, and CD14
Waldmann et al., Int Rev Immunol 1998 : In mast cells, IL-15 signaling involves JAK-2 and STAT-5 activation rather than the JAK-1 and JAK-3 as well as the STAT-3 and STAT-5 used by both IL-2 and IL-15 in activated T cells