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CCND1 — TGFB1

Text-mined interactions from Literome

Wenner et al., Braz J Med Biol Res 1999 (Cell Transformation, Neoplastic) : TGF-beta 1 delayed EGF- or PDGF induced cyclin D1 expression and blocked the induction of active p42/p44MAPK
Cospedal et al., Biochem J 1999 : TGF-beta(1) had no effect on the expression of c-myc or p27 ( kip1 ) and weakly attenuated the expression of cyclin D(1)
Kornmann et al., Int J Cancer 1999 (Pancreatic Neoplasms) : In the present study, we investigated the effects of TGF-beta1 on cyclin D1 expression and activity in COLO-357 human pancreatic cancer cells ... Despite its stimulatory effects on cyclin D1 levels, TGF-beta1 inhibited cyclin D1-associated kinase activity and the growth of COLO-357 cells
Choi et al., J Biol Chem 1999 (Liver Neoplasms, Experimental) : TGF-beta1 induced a transient increase in the expression of Cdc2, cyclin A, cyclin B, and cyclin D1 at an early phase of apoptosis
Lang et al., J Am Soc Nephrol 2000 (Glomerulonephritis, Membranoproliferative...) : Transforming growth factor-beta1 inhibited PDGF induction of cyclin D1 protein at 12 h
Roy et al., Circ Res 2003 (Hyperoxia) : The molecular signature response to perceived hyperoxia included ( 1 ) induction of p21, cyclin D1 , cyclin D2, cyclin G1, Fos related antigen-2, and transforming growth factor-beta1, ( 2 ) lowered telomerase activity, and ( 3 ) activation of transforming growth factor-beta1 and p38 mitogen activated protein kinase
Shi et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2004 : ( 2 ) 2 ng/ml TGF-beta1 could significantly inhibit the production of cyclin A, cyclin D1 , CDK2 and CDK4, the protein levels were significantly lower than control group
Ko et al., Oncogene 1995 : Transforming growth factor-beta 1 inhibits cyclin D1 expression in intestinal epithelial cells
Okamoto et al., Proc Natl Acad Sci U S A 1994 : Overexpression of human cyclin D1 reduces the transforming growth factor beta ( TGF-beta) type II receptor and growth inhibition by TGF-beta 1 in an immortalized human esophageal epithelial cell line
Sugiyama et al., Biochem Biophys Res Commun 1997 : We investigated the effects of TGF-beta1 on cyclin D1 , cyclin A, p21, p27, and p53 mRNA expressions in primary cultured rat hepatocytes by the reverse-transcription polymerase chain reaction ( RT-PCR ) method
Ko et al., Oncogene 1998 : Transforming growth factor-beta 1 ( TGF-beta1 ) arrests intestinal epithelial cells ( RIE-1 and IEC-6 ) in the G1 phase of the cell cycle and inhibits cyclin D1 expression ... Metabolic labeling studies indicated that TGF-beta1 inhibited cyclin D1 synthesis without altering the rate of cyclin D1 protein degradation ... These data indicate that TGF-beta1 inhibits the synthesis of cyclin D1 in gut epithelial cells and that this inhibition is the cause, rather than the result, of TGF-beta1 mediated arrest of intestinal epithelial cell proliferation