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MYLIP — RHOB

Text-mined interactions from Literome

Glorian et al., Cell Death Differ 2011 : Here we report that miR-19 , an oncogenic component of the miR-17-92/Oncomir-1 microRNA polycistron, regulates the expression of Ras homolog B (RhoB) in keratinocytes upon exposure to ultraviolet ( UV ) radiation ... However, we show that miR-19 mediated regulation of antiapoptotic RhoB expression requires the binding of human antigen R (HuR), an AU-rich element binding protein, to the 3'-untranslated region of the rhoB mRNA
Liu et al., FEBS Lett 2011 (Colorectal Neoplasms...) : miR-21 expression significantly suppressed RhoB 3 ' UTR luciferase-reporter activity, but the inhibitory effect was lost when the putative target sites were mutated
Parikh et al., Circulation 2012 (Hypertension, Pulmonary) : Furthermore, miR-21 directly represses RhoB expression and Rho-kinase activity, inducing molecular changes consistent with decreased angiogenesis and vasodilation
Yang et al., Biochem Biophys Res Commun 2013 (Colitis, Ulcerative) : Furthermore, miR-21 induced the degradation of RhoB mRNA, which led to the depletion of RhoB and the impairment of tight junctions in intestinal epithelial cells
Shi et al., PloS one 2013 (Colitis...) : Finally, we found that miR-21 regulated the intestinal barrier function through modulating the expression of RhoB and CDC42