UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to SMAD6

HFE2 — SMAD6

Pathways - manually collected, often from reviews:

NCI Pathway Database BMP receptor signaling: BMP2-4/BMPR2/BMPR1A-1B/RGM/XIAP complex (BMP4_BMP2-BMPR2-BMPR1A_BMPR1B-RGMB_RGMA_HFE2-XIAP) → TAK1/SMAD6 complex (MAP3K7-SMAD6) (modification, activates)
Kimura et al., J Biol Chem 2000, Yamaguchi et al., EMBO J 1999
Evidence: mutant phenotype, physical interaction