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CTNNB1 — TGFB1

Text-mined interactions from Literome

Janji et al., Int J Cancer 1999 (Melanoma) : Our data further illustrate the TGF-beta1 dependent up-regulation of integrin linked kinase and the nuclear translocation of beta-catenin , 2 intracellular proteins involved in integrin and cadherin signaling
Xu et al., Cell Res 2003 (Carcinoma, Hepatocellular...) : Furthermore, TGF-beta1 induced the down-regulation of E-cadherin and the nuclear translocation of beta-catenin
Cheon et al., Exp Cell Res 2004 (Cicatrix) : EGF and TGF-beta1 significantly increased beta-catenin protein levels and transcriptional activity, whereas beta-catenin mRNA expression was unaffected
Edlund et al., Mol Cell Biol 2005 (Prostatic Neoplasms) : Smad7 was found to be required for TGF-beta1 induced accumulation of beta-catenin and LEF1 in human prostate cancer ( PC-3U ) cells as well as in human keratinocytes ( HaCaT cells )
Cordray et al., Dev Dyn 2005 : We recently identified and characterized a novel Wnt-like effect of transforming growth factor-beta ( TGF-beta ) on beta-catenin , the binding partner of Lef-1
Vogelmann et al., J Cell Sci 2005 : By contrast, forced expression of PTEN clearly reduced the TGFbeta(1) induced phosphorylation of beta-catenin ... The TGFbeta(1) induced beta-catenin phosphorylation was also dependent on PI3-kinase and Ras activity
Jian et al., Genes Dev 2006 : We show that TGF-beta1 induces rapid nuclear translocation of beta-catenin in MSCs in a Smad3 dependent manner
Caraci et al., Pharmacol Res 2008 : At this time, TGF-beta1 also increased the total levels of beta-catenin , an effect that was prevented by PD98059
Clifford et al., J Biol Chem 2008 : Finally, we demonstrate that TGFbeta(1) regulates TCF by modifying beta-catenin phosphorylation via regulation of glycogen synthase kinase 3beta
Tanwar et al., Biol Reprod 2009 (Cell Transformation, Neoplastic...) : By immunohistochemistry, we also show that both transforming growth factor beta and the mammalian target of rapamycin are induced by constitutive activation of beta-catenin
Poon et al., BMC cell biology 2009 : Both signaling pathways positively regulate fibroblast proliferation during this reparative process, and the effect of transforming growth factor beta is partially mediated by beta-catenin ... In contrast to the situation in the regulation of cell proliferation, this effect of transforming growth factor beta was not mediated by beta-catenin
Vi et al., BMC musculoskeletal disorders 2009 (Dupuytren Contracture) : The aim of this study was to determine if a collagen enriched environment, similar to in vivo conditions, altered beta-catenin accumulation by primary DD cells in the presence or absence of transforming growth factor-beta
Zheng et al., Am J Pathol 2009 (Fibrosis) : TGF-beta1 induced the proteolytic shedding of E-cadherin, which caused the nuclear translocation of beta-catenin , the transcriptional induction of Slug, and the repression of E-cadherin transcription in tubular epithelial cells
Wincewicz et al., Pathol Oncol Res 2010 (Colorectal Neoplasms) : Beta-catenin accumulation is suppressed by TGF-beta1 ( transforming growth factor beta1 ) in intestinal epithelium suggesting negative feedback between these two factors
Zhang et al., J Biol Chem 2010 : Our previous study demonstrated that transforming growth factor ( TGF ) -beta activates beta-catenin signaling through Smad3 interaction with beta-catenin in chondrocytes
He et al., J Biol Chem 2010 (MAP Kinase Signaling System) : TGF-beta1 stimulated beta-catenin activation in tubular epithelial cells, and ectopic expression of beta-catenin induced PAI-1 expression, whereas inhibition of beta-catenin abolished its induction
Liu et al., Sichuan Da Xue Xue Bao Yi Xue Ban 2011 : Real-time PCR and Western blot demonstrated that 1 micromol/L TGF-beta1 could increase the expression of beta-catenin ; C3a and C5a presented the similar inducible effect as TGF-beta1, which could be blocked by C3aR antagonist and C5aR antagonist ( C3aRA and C5aRA )