Gene interactions and pathways from curated databases and text-mining

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DST — IGF1R

Text-mined interactions from Literome

Jenkins et al., Environ Health Perspect 2011 (Cell Transformation, Neoplastic...) : At the molecular level, 25 µg BPA/L, but not 2,500 µg BPA/L , increased phosphorylation of erbB2, erbB3, insulin-like growth factor 1 receptor , and Akt in the mammary gland
Kang et al., Food Chem Toxicol 2013 (Ovarian Neoplasms) : BPA induced a significant increase in BG-1 cell growth and up-regulated mRNA levels of ERa and IGF-1R