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FGFR1 — PDGFB

Pathways - manually collected, often from reviews:

• KEGG Prostate cancer: EGF/IGF1/INS/PDGFA/PDGFB/PDGFC/PDGFD/TGFA → EGFR/ERBB2/FGFR1/FGFR2/IGF1R/INSRR/PDGFRA/PDGFRB (protein-protein, activation)
  
• KEGG Melanoma: EGF/FGF1/FGF10/FGF11/FGF12/FGF13/FGF14/FGF16/FGF17/FGF18/FGF19/FGF2/FGF20/FGF21/FGF22/FGF23/FGF3/FGF4/FGF5/FGF6/FGF7/FGF8/FGF9/HGF/IGF1/PDGFA/PDGFB/PDGFC/PDGFD → EGFR/FGFR1/IGF1R/MET/PDGFRA/PDGFRB (protein-protein, activation)
  
• WikiPathways Focal Adhesion-PI3K-Akt-mTOR-signaling pathway: EFNA1/FGF1/FGF11/FGF10/EFNA2/EGF/FGF12/CSF1/ANGPT4/ANGPT2/ANGPT1/VEGFA/EFNA3/EFNA4/EFNA5/FGF14/FGF19/FGF17/FGF18/FGF2/FGF3/FGF4/FGF6/FGF7/FGF8/FGF9/FIGF/HGF/IGF1/INS/INS/KITLG/VEGFC/VEGFB/PDGFB/PGF/PDGFA/NGF/PDGFC/FGF21/FGF22/PDGFD/FGF20/FGF16 → FGFR2/KDR/INSR/FGFR3/IGF1R/KIT/FGFR1/EPHA2/EGFR/CSF1R/FGFR4/FLT1/FLT4/NGFR/MET/PDGFRA/PDGFRB/TEK (activation)
  

Text-mined interactions from Literome

Millette et al., Circ Res 2005 : A bFGF neutralizing antibody inhibited PDGF-BB mediated phosphorylation of FGFR-1 , DNA synthesis, and cell proliferation ... Our results provide support for a novel mechanism by which PDGF-BB induces the release of bFGF and activation of FGFR-1 followed by the sustained activation of ERK and proliferation of human SMCs
Faraone et al., Blood 2006 : In this study, we report that PDGF-BB inhibits a series of FGF-2 induced events, such as proliferation of human umbilical vein endothelial cells ( HUVECs ), FGF-2 cellular internalization, phosphorylation of intracellular signaling factors including p38, rac1/cdc42, MKK4, and MKK3/6, and phosphorylation of FGF-receptor 1 (FGF-R1)
Chen et al., J Biol Chem 2009 : Furthermore, we show that PDGF-BB induces tyrosine phosphorylation of FGFR1 and that this phosphorylation is mediated by PDGF receptor-beta ( PDGFRbeta ), but not c-Src