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CNR2 — EPHB2
Text-mined interactions from Literome
Zhao et al., J Biol Chem 2005
(Cell Transformation, Neoplastic) :
Whether
cannabinoid receptor 2 (CB2) is
involved in 2-AG induced
ERK activation is still unclear
Franklin et al., Pharmacol Res 2013
:
Additionally, inhibition of clathrin mediated endocytosis,
ERK1/2 , and the AP-1 transcription factor also
prevented the
cannabinoid receptor induced upregulation of ß-Arrestin 2 ... The
CB(2) receptor mediated upregulation of ß-Arrestin 2 would be
mediated , at least in part, by an
ERK1/2 dependent activation of AP-1
Franklin et al., J Biol Chem 2013
(MAP Kinase Signaling System) :
Our results suggest that sustained activation of
CB2 receptors, which up-regulates 5-HT2A receptor signaling,
enhances GRK5 expression ; the phosphorylation of CB2 receptors ; and the ß-arrestin
2/ERK interactions