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ANG — CCL2
Text-mined interactions from Literome
Ortego et al., Atherosclerosis 1999
(Coronary Artery Disease...) :
Ang II and TNF-alpha
induced the expression of IP-10 ( 1.5 and 3.4-fold ) and
MCP-1 ( 2.4 and 4-fold ) in VSMC
Satonaka et al., Circ Res 2004
(Calcium Signaling...) :
Angiotensin II (Ang II) also significantly
stimulated MCP-1 expression, and this increase was significantly inhibited by cyclosporin A ( CyA )
Yamagishi et al., Cell Tissue Res 2005
:
Ang II significantly
induced redox-sensitive transcriptional factor NF-kappaB activation and subsequent
monocyte chemoattractant protein-1 expression in human umbilical vein ECs ( HUVEC ), both of which were completely inhibited by PEDF or the anti-oxidant N-acetylcysteine
Kanno et al., Dig Dis Sci 2005
(Hepatitis...) :
These results suggest that Ang II modulates hepatic inflammation via production of MCP-1 by hepatic stellate cells, and the
effect of
Ang II on
MCP-1 production is, at least partly, mediated by the Rho/Rho-kinase pathway
Wu et al., J Hypertens 2006
:
The effect of nifedipine, a 1,4-dihydropyridine calcium antagonist, on the expression of
monocyte chemoattractant protein 1 ( MCP-1 )
induced by
angiotensin II (Ang II) was examined using vascular smooth muscle cells ( VSMC ) isolated from rat thoracic aorta ... Nifedipine decreased MCP-1 mRNA expression, together with NF-kappaB binding activity to the promoter region of
MCP-1 induced by
Ang II
Tsuchiya et al., Am J Physiol Endocrinol Metab 2006
(Obesity) :
The present study was undertaken to investigate the potential mechanisms by which
ANG II
affects MCP-1 gene expression in rat primary cultured preadipocytes and adipose tissue in vivo
Miura et al., J Pharmacol Sci 2006
:
Alacepril, CV-11974, and spironolactone significantly reduced the enhanced production of
MCP-1 and TNF-alpha
induced by exogenous
Ang II
Lee et al., Nephrol Dial Transplant 2007
(Diabetes Mellitus, Experimental...) :
COMP-Ang1 suppressed both renal expression of intercellular adhesion molecule-1 and
monocyte chemoattractant protein-1 and monocyte/macrophage infiltration in diabetic db/db mice
Ko et al., Vascul Pharmacol 2007
(Inflammation) :
Among the chemokines,
monocyte chemoattractant protein (MCP)-1 induced by
Ang II acts as a central mediator of the inflammatory responses ... Berberine, a major component of Coptis chinensis Franch, also showed similar effects on ROS production and
MCP-1 expression
induced by
Ang II
Guo et al., Arch Med Res 2008
(Cardiovascular Diseases) :
Collectively, these results indicated that ACE2 overexpression in the THP-1 attenuates AngII induced
MCP-1 production and that this reduction is likely
mediated by increased
Ang ( 1-7 ) level
Lee et al., Nephrol Dial Transplant 2008
(Kidney Diseases) :
CsA induced increases in macrophage infiltration and expression of
MCP-1 and ICAM-1 after CsA treatment were significantly
reduced by
COMP-Ang1
Ding et al., World journal of pediatrics : WJP 2010
:
We investigated the role of c-Jun NH2-terminal kinase (JNK), a member of the mitogen activated protein kinase family, in the expression of
angiotensin II (Ang II) induced
monocyte chemoattractant protein-1 ( MCP-1 ) and transforming growth factor-1 ( TGF-1 ), and in the production of fibronectin ( FN ), by human mesangial cells ( HMCs )
Chen et al., Circ Res 1998
:
To investigate a potential molecular basis for a link between hypertension and atherosclerosis, we studied the
effects of
angiotensin II (Ang II) on
MCP-1 gene expression in rat aortic smooth muscle cells