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CDK8 — HRAS
Text-mined interactions from Literome
Kremerskothen et al., Neurosci Lett 2002
(Neuroblastoma) :
Insulin induced expression of the activity regulated cytoskeleton associated gene (
ARC ) in human neuroblastoma cells
requires p21(ras) , mitogen activated protein kinase/extracellular regulated kinase and src tyrosine kinases but is protein kinase C-independent
Teramoto et al., Oncogene 2003
:
For example, H-Ras V12 upregulated osteopontin and Akt 1, and
H-Ras and RhoA
stimulated cyclin G1,
cyclin dependent kinase 8, cyclin A2 and HMGI-C, while Rac1 QL and Cdc42 QL upregulated extracellular matrix and cell adhesion proteins such as alpha-actinin 4, procollagen type I and V and neuropilin