Gene interactions and pathways from curated databases and text-mining

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CD40LG — SELE

Text-mined interactions from Literome

Jollow et al., Transplantation 1999 : CD40-CD40L interactions induced the expression of the adhesion molecules VCAM-1 and E-selectin and the costimulatory molecule CD80 but not CD86 ( B7-2 ) on the MECs
Wang et al., Circulation 2002 (Coronary Artery Disease) : Long-term CD154 blockade also suppressed endothelial E-selectin , P-selectin, and intracellular adhesion molecule-1 expression and improved graft function 3.5-fold versus control ( P < 0.05 )
Zhu et al., Transplant Proc 2008 : FACS demonstrated upregulation of EC-derived CD62E expression induced by CD154 expressing D1.1 cells
Xia et al., Zhonghua Yi Xue Za Zhi 2008 (MAP Kinase Signaling System) : [ Inhibition of CD40L induced E-selectin expression in endothelial cells through extracellular signal regulated kinase signaling pathway ] ... Atorvastatin decreases the CD40L induced E-selectin expression in endothelial cells while atorvastatin at 0.1-10 micromol/L concentration-dependently through inhibiting the activation of ERK1/2