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CDKN1A — CDX2

Text-mined interactions from Literome

Bai et al., Oncogene 2003 (Carcinoma...) : CDX2 , a homeobox transcription factor, upregulates transcription of the p21/WAF1/CIP1 gene ... Moreover, overexpression of CDX2 increased the mRNA expression of p21 in HT-29 colon carcinoma cells, as demonstrated by reverse transcription-polymerase chain reaction
Saegusa et al., Carcinogenesis 2007 (Endometrial Neoplasms) : These data suggest that over-expression of Cdx2 mediated by nuclear beta-catenin and Cdx2 itself can cause an inhibition of Em Ca cell proliferation through up-regulation of p21 ( Waf1 ) expression, modulating beta-catenin/TCF4 mediated transcription