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TCF3 — TGFB1
Text-mined interactions from Literome
Prasad et al., J Am Coll Nutr 1999
(Neoplasms) :
The proposed mechanisms for these effects include inhibition of protein kinase C activity, prostaglandin E1-stimulated adenylate cyclase activity, expression of c-myc, H-ras, and a
transcription factor ( E2F ), and
induction of
transforming growth factor-beta and p21 genes
Palcy et al., J Bone Miner Res 2000
:
Our data emphasize the
role of the AP-1
transcription factor in
TGF-beta1 and BMP-2 signaling and highlight the importance of this transcription factor family in the expression of OB genes
Peinado et al., J Biol Chem 2003
(MAP Kinase Signaling System) :
Transforming growth factor beta-1 induces snail
transcription factor in epithelial cell lines : mechanisms for epithelial mesenchymal transitions
Funaba et al., J Biol Chem 2003
:
Transcriptional activation of mouse mast cell Protease-7 by activin and
transforming growth factor-beta is
inhibited by microphthalmia associated
transcription factor
Singh et al., American journal of physiology. Renal physiology 2004
:
Similarly,
TGF-beta1 and hexosamines
led to nonadditive increases in phosphorylation of the cAMP responsive element binding
transcription factor
Lee et al., J Exp Clin Cancer Res 2003
:
Effect of ets related
transcription factor ( ERT ) on
transforming growth factor ( TGF)-beta type II receptor gene expression in human cancer cell lines
Sieczkiewicz et al., Microvasc Res 2003
:
TGF-beta 1 induces expression of the myogenic
transcription factor myf-5 and the cyclin dependent kinase inhibitor p27 ; we show that these signaling pathways are disrupted in the DNT beta RII bearing pericytes
Kim et al., Int J Biochem Cell Biol 2004
(MAP Kinase Signaling System) :
We also found that
TGF-beta1 reduces microphthalmia associated
transcription factor ( MITF ) promoter activity and decreased MITF, tyrosinase, tyrosinase related protein-1 (TRP-1), and TRP-2 protein production
Murakami et al., Cell Signal 2006
:
Microphthalmia associated
transcription factor ( MITF ), a member of the basic helix-loop-helix leucine zipper family of tissue-specific transcription factors predominantly expressed in mast cells, melanocytes and osteoclasts, also stimulated PAI-1 gene transcription, and
TGF-beta1 did not
increase PAI-1 mRNA levels in mast cells from mi/mi mice expressing dominant negative MITF
Chiarpotto et al., Biofactors 2005
(Fibrosis) :
In fact, 4-hydroxy-2,3-nonenal ( HNE ), the major aldehydic product of lipid peroxidation, is able to induce
TGFbeta1 expression and synthesis, and
activation of activator protein-1 (AP-1)
transcription factor
Zhang et al., Am J Pathol 2006
:
In contrast inhibition of p38 MAP kinase inhibited de novo TGF-beta1 protein synthesis but did not influence
TGF-beta1 mRNA expression or
activation of either
transcription factor
Ohtsuki et al., Mol Cell Biol 1992
:
Transforming growth factor-beta 1 ( TGF-beta 1 ) rapidly
increases the expression of junB
transcription factor and plasminogen activator inhibitor-1 ( PAI-1 ) and prevents the cell cycle dependent phosphorylation of the RB retinoblastoma susceptibility gene product during late G1 phase in Mv1Lu lung epithelial cells
Kaimori et al., J Biol Chem 2007
:
We also show that in hepatocytes in the EMT state,
TGF-beta1 induces the snail-1
transcription factor and activates the Smad2/3 pathway
Herrmann et al., Biochim Biophys Acta 2007
:
In the present study we found that during cellular activation and transdifferentiation the SRF
transcription factor is
up-regulated by
transforming growth factor-beta , accumulated in the nucleus, and exhibited increased DNA binding activity
Lee et al., American journal of physiology. Renal physiology 2008
:
Sevoflurane and
TGF-beta1 caused the nuclear translocation of the SMAD3
transcription factor in HK-2 cells
Chen et al., Immunol Res 2008
(Bacterial Infections) :
In the mouse, the differentiation of this new lineage is initiated by
TGFbeta-1 and IL-6 and IL-21, which activate Stat3 and
induce the expression of the
transcription factor retinoic acid related orphan receptor ( RORgammat )
Clifford et al., J Biol Chem 2008
:
Finally, we demonstrate that
TGFbeta(1) regulates
TCF by modifying beta-catenin phosphorylation via regulation of glycogen synthase kinase 3beta
Herzinger et al., Oncogene 1995
:
We have studied the
effect of
TGF-beta 1 on protein binding to a
transcription factor E2F consensus element in extracts from early passage human keratinocytes ( HFKs ) and a permanent human keratinocyte cell line ( HaCaT )
Alevizopoulos et al., J Biol Chem 1996
:
Antagonistic
regulation of a proline-rich
transcription factor by
transforming growth factor beta and tumor necrosis factor alpha