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IL17D — SOAT1

Text-mined interactions from Literome

Kamiya et al., J Immunol 2004 : These results suggest that IL-27 activates JAK1 and -2, tyrosine kinase-2, STAT1 , -2, -3, and -5 in naive CD4+ T cells and that STAT1 plays an indispensable role in IL-27 induced T-bet and subsequent IL-12Rbeta2 expression and MHC class I expression as well but not proliferation, while STAT3 presumably plays an important role in IL-27 induced proliferation
Yoshimura et al., J Immunol 2006 : In fully activated CD4+ T cells, STAT3 was preferentially activated by IL-27 stimulation, whereas both STAT1 and 3 were activated by IL-27 in early activated CD4+ T cells
Seita et al., Blood 2008 : Interleukin (IL)-27 , one of the most recently discovered IL-6 family cytokines, activates both the signal transducer and activator of transcription ( STAT ) 1 and STAT3, and plays multiple roles in pro- and anti-inflammatory immune responses