UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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LRPPRC — SOS1

Pathways - manually collected, often from reviews:

BioCarta il 6 signaling pathway: IL-6/IL-6/IL-6R-alpha/IL-6R-alpha/GP130/GP130/JAKS complex (JAK2_JAK1_JAK3-LRPPRC-IL6R-IL6) → SHC/GRB2/SOS-1 complex (SOS1-GRB2-SHC1) (modification, activates)