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PKD2 — SRC

Text-mined interactions from Literome

Waldron et al., J Biol Chem 2000 : Genistein, or the specific Src inhibitors PP-1 and PP-2 ( 1-10 micrometer ) inhibited H ( 2 ) O ( 2 ) -mediated PKD activation by 45 %, indicating that Src contributes to this signaling pathway
De Kimpe et al., Cell Signal 2009 : Src , a well-known cortactin kinase, strongly potentiated the in vivo PKD mediated cortactin phosphorylation ... This Src effect is neither mediated by pre-phosphorylation of cortactin nor by activation of PKD by Src
Arun et al., Oncogene 2011 : Thus, our data indicate that UVB irradiation of keratinocytes induces Src mediated activation of PKD , which protects cells from UVB stimulated apoptosis, providing a possible explanation for the observed upregulation of PKD in BCC