Gene interactions and pathways from curated databases and text-mining

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EDN1 — NUP43

Text-mined interactions from Literome

Kawamura et al., Bone 1999 : Endothelin-1 stimulated p42/p44 MAP kinase activation in a dose dependent manner in the range between 0.1 nmol/L and 0.1 micromol/L. PD98059, a specific inhibitor of the upstream kinase that activates p42/p44 MAP kinase, suppressed endothelin-1 induced IL-6 synthesis as well as endothelin-1 activated p42/p44 MAP kinase ... Calphostin C, a highly specific inhibitor of protein kinase C, suppressed endothelin-1 stimulated p42/p44 MAP kinase activation as well as endothelin-1 induced IL-6 synthesis
Yang et al., Blood 2003 : EDN also induced the activation of p42/44 mitogen activated protein kinase ( MAPK ) in DCs
Peng et al., Pflugers Arch 2012 : N-Acetyl-seryl-aspartyl-lysyl-proline ( Ac-SDKP ) inhibits endothelin-1 (ET-1) induced activation of p44/42 mitogen activated protein kinase ( p44/42 MAPK ) and collagen production in cultured rat cardiac fibroblasts ( RCFs )
Wang et al., J Cardiovasc Pharmacol 1993 : We have reported that endothelin-1 (ET-1) , which is a constrictor and mitogenic peptide, can increase mitogen activated protein kinase p42 ( p42mapk ) activity in rat mesangial cells